SCHEMBL8670753

SCHEMBL8670753

CCc1ccc2c(c1)-c1ccccc1C2=O

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.89
NPC1 O15118 6/20 0.89
RAB9A P51151 6/20 0.89
LMNA P02545 5/20 0.89
SMN1; SMN2 Q16637 5/20 0.89
MAPK1 P28482 4/20 0.89
ALDH1A1 P00352 3/20 0.89
L3MBTL1 Q9Y468 3/20 0.89
ELANE P08246 1/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CDC25B P30305 1/20 0.48
ATM Q13315 2/20 0.47
CASP3 P42574 2/20 0.47
SENP8 Q96LD8 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP6 Q9GZR1 2/20 0.47
PTPRC P08575 3/20 0.47
APAF1 O14727 3/20 0.46
S100A4 P26447 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7318179 0.96 NPC1 (0.96) MAPTNPC1RAB9ALMNASMN1; SMN2
9,10-Phenanthrenequinone SCHEMBL6059381 0.94 NPC1 (0.92) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL29352712 0.94 NPC1 (1.00) MAPTNPC1RAB9ALMNASMN1; SMN2
Anthraquinone SCHEMBL6310187 0.94 NPC1 (1.00) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL36840 0.94 NPC1 (1.00) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL27590795 0.92 NPC1 (0.96) MAPTNPC1RAB9ALMNASMN1; SMN2
Water SCHEMBL28061572 0.92 NPC1 (0.96) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL13437909 0.92 SMN1; SMN2 (0.80) MAPTNPC1RAB9ALMNASMN1; SMN2
Formaldehyde SCHEMBL28131826 0.90 NPC1 (0.92) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL19396241 0.87 SMN1; SMN2 (0.88) MAPTNPC1RAB9ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115528215-A Secondary battery positive electrode material pre-ionization reagent and preparation method and application thereof 深圳珈钠能源科技有限公司 2022-12-27 CN claimed
CN-115528215-A Secondary battery positive electrode material pre-ionization reagent and preparation method and application thereof 深圳珈钠能源科技有限公司 2022-12-27 CN disclosed
US-9637565-B2 Photoinitiating system for anionic polymerization UVIC INDUSTRY PARTNERSHIPS INC. (US) 2017-05-02 US disclosed
US-20080280905-A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS BRISTOL MYERS SQUIBB COMPANY (US) 2008-11-13 US disclosed
EP-0886182-A1 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280905-A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS P2RY1, P2RY11, P2RY2 MAPT 3475/4885NPC1 2764/4885RAB9A 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.