SCHEMBL8670784

SCHEMBL8670784

CN1CCC/C1=N/c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 2/20 0.50
HPGD P15428 1/20 0.50
LMNA P02545 3/20 0.39
ALOX15 P16050 1/20 0.39
GRM5 P41594 1/20 0.38
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
TNKS O95271 1/20 0.35
PARP1 P09874 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
INMT O95050 2/20 0.34
BRD4 O60885 1/20 0.34
BRD2 P25440 1/20 0.34
TTR P02766 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8670787 1.00 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL18806077 0.94 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL18806078 0.93 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL7327876 0.84 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL7327868 0.84 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL11312615 0.81 KDM4E (0.42) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL11312618 0.81 KDM4E (0.42) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL10341763 0.78 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL10341764 0.78 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDLMNAALOX15
SCHEMBL14368030 0.77 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDLMNAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807962-A POLYCARBONATES; SOLVENT RESISTANCE; FIREPROOFING THE DOW CHEMICAL COMPANY (US) 1998-09-15 US disclosed
US-5674968-A Aromatic sulfonated diester monomer, process to synthesize, polymer derived therefrom and method to prepare said polymer THE DOW CHEMICAL COMPANY (US) 1997-10-07 US disclosed
US-5543448-A CONTAINING A BLOCK ADDITION POLYMER THE DOW CHEMICAL COMPANY (US) 1996-08-06 US disclosed
US-5539030-A POLYMER BLENDS FOR MOLDING MATERIALS THE DOW CHEMICAL COMPANY (US) 1996-07-23 US disclosed
EP-0630392-A1 POLYMERS AND POLYMER BLENDS MODIFIED WITH POLY(PHENYLENE ETHER) THE DOW CHEMICAL COMPANY (US) 1994-12-28 EP disclosed
US-5362841-A Controlling ph, coupling catalyst THE DOW CHEMICAL COMPANY (US) 1994-11-08 US disclosed
US-5362839-A Dissolving carbonate oligomers, mixing with chain terminators and reacting to form polycarbonates THE DOW CHEMICAL COMPANY (US) 1994-11-08 US disclosed
WO-1994018258-A1 PROCESS FOR PREPARING POLYCARBONATE HAVING REDUCED CARBONATE BYPRODUCT CONTENT THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO disclosed
US-5321116-A From ortho substituted dihydric phenol and nonortho substituted dihydric phenol THE DOW CHEMICAL COMPANY (US) 1994-06-14 US disclosed
US-5321115-A Phenolic endcapped oligomers; coupling catalyst; heat resistance THE DOW CHEMICAL COMPANY (US) 1994-06-14 US disclosed
US-5258432-A Polyester, (meth)acrylate homopolymer, polytetrafluoroethylene, organophosphorus compound and an aromatic halogenated carbonate oligomer THE DOW CHEMICAL COMPANY (US) 1993-11-02 US disclosed
WO-1993019128-A2 POLYMERS AND POLYMER BLENDS MODIFIED WITH POLY(PHENYLENE ETHER) THE DOW CHEMICAL COMPANY (US) 1993-09-30 WO disclosed
WO-1993018090-A1 IGNITION RESISTANT POLYCARBONATE BLENDS THE DOW CHEMICAL COMPANY (US) 1993-09-16 WO disclosed
EP-0552352-A1 PROCESS FOR THE PREPARATION OF HIGH MOLECULAR WEIGHT HALOGENATED POLYCARBONATE THE DOW CHEMICAL COMPANY (US) 1993-07-28 EP disclosed
US-5218078-A Catalytic emulsion polymerizations of halogenated dihydroxy compounds in aqueous mixtures containing base and organic solvents, two-stage polymerizations THE DOW CHEMICAL COMPANY (US) 1993-06-08 US disclosed
US-5212282-A Esterification, oligomerization, interfacial polymerization THE DOW CHEMICAL COMPANY (US) 1993-05-18 US disclosed
US-5200496-A Adding chain terminator and catalyst to control molecular weight THE DOW CHEMICAL COMPANY (US) 1993-04-06 US disclosed
WO-1993003083-A1 PROCESS FOR THE PREPARATION OF HIGH MOLECULAR WEIGHT HALOGENATED POLYCARBONATE THE DOW CHEMICAL COMPANY (US) 1993-02-18 WO disclosed
WO-1993002123-A1 PROCESS FOR PREPARING HALOGENATED POLYCARBONATE THE DOW CHEMICAL COMPANY (US) 1993-02-04 WO disclosed
US-4277598-A HIGH MOLECULAR WEIGHT POLYCARBONATES BY INTERFACIAL POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 1981-07-07 US disclosed