Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | SOX18 | P35713 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240981 | 0.93 | CYP1A2 (0.65) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A | |
| SCHEMBL29560700 | 0.93 | CYP1A2 (0.65) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A | |
| SCHEMBL3024493 | 0.91 | CYP1A2 (0.65) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A | |
| SCHEMBL3941594 | 0.91 | CYP1A2 (0.65) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A | |
| SCHEMBL29477161 | 0.91 | CYP1A2 (0.65) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A | |
| SCHEMBL28746131 | 0.85 | CYP1A2 (0.58) | PLAUCYP1A2CYP2A6SIGMAR1HRH3 | |
| SCHEMBL9827506 | 0.85 | MAOB (0.61) | PLAUCYP1A2CYP2A6SIGMAR1HRH3 | |
| SCHEMBL13946261 | 0.85 | CYP2A6 (0.58) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A | |
| SCHEMBL21517641 | 0.85 | ESR1 (0.58) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A | |
| SCHEMBL6295016 | 0.84 | CYP1A2 (0.56) | PLAUCYP1A2CYP2A6SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410116-B2 | Compounds and use thereof in methods of treatment | THE UNIVERSITY OF QUEENSLAND (AU) | 2025-09-09 | — | — | US | disclosed |
| CN-115772058-B | Reduction method of aromatic internal olefins | 南通大学 | 2024-08-16 | — | — | CN | disclosed |
| US-20240002326-A1 | COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT | THE UNIVERSITY OF QUEENSLAND (AU) | 2024-01-04 | — | — | US | disclosed |
| CN-114345370-B | Method for reduction cross coupling of photocatalytic aromatic olefin and halogenated hydrocarbon | 陕西师范大学 | 2023-07-21 | — | — | CN | disclosed |
| US-20230100768-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2023-03-30 | — | — | US | disclosed |
| CN-115772058-A | Reduction method of aromatic internal olefin | 南通大学 | 2023-03-10 | — | — | CN | disclosed |
| US-11434190-B2 | Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-09-06 | — | — | US | disclosed |
| CN-114345370-A | Method for reducing and cross-coupling aromatic olefin and halogenated hydrocarbon through photocatalysis | 陕西师范大学 | 2022-04-15 | — | — | CN | disclosed |
| US-20190337880-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS-AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2019-11-07 | — | — | US | disclosed |
| CN-101175713-B | Acrylic ester compound and manufacturing intermediate thereof, method for manufacturing acrylic ester compound, and latent electrostatic image bearing member, image forming method, image forming apparatus and photocopying cartridge | RICOH CO LTD | 2013-05-15 | — | — | CN | disclosed |
| CN-101175713-A | Acrylic ester compound and manufacturing intermediate thereof, method for manufacturing acrylic ester compound, and latent electrostatic image bearing member, image forming method, image forming appar | RICOH KK (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1291958-C | Naphthacridine derivative and liquid crystal composite containing it | DAINIPPON INK CHEMICAL IND CO (JP) | 2006-12-27 | — | — | CN | disclosed |
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337880-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS-AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | SOX18, PROX1, RUNX1 | PLAU 1902/4885CYP1A2 4690/4885CYP2A6 4670/4885 |
| US-11434190-B2 | Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases | SOX18, PROX1, RUNX1 | PLAU 1902/4885CYP1A2 4690/4885CYP2A6 4670/4885 |
| US-20230100768-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | SOX18, PROX1, RUNX1 | PLAU 1932/4885CYP1A2 4661/4885CYP2A6 4688/4885 |
| US-12410116-B2 | Compounds and use thereof in methods of treatment | SOX18, PROX1, RUNX1 | PLAU 1921/4885CYP1A2 4644/4885CYP2A6 4617/4885 |
| US-20240002326-A1 | COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT | SOX18, PROX1, RUNX1 | PLAU 1921/4885CYP1A2 4644/4885CYP2A6 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.