Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 14/20 | 0.56 |
| ▸ | BCHE | P06276 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669649 | 0.88 | ALDH1A1 (0.66) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL14197657 | 0.88 | ALDH1A1 (0.56) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL21243268 | 0.86 | CYP1A2 (0.55) | CHRM2BCHEACHEGRIN1GRIN2A | |
| SCHEMBL27728063 | 0.83 | CHRM2 (0.55) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL31367150 | 0.83 | CHRM2 (0.52) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL8387661 | 0.81 | HTR1B (0.60) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918374 | 0.81 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918881 | 0.81 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918894 | 0.81 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL21243277 | 0.80 | CYP1A2 (0.51) | TP53CYP3A4TSHRMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853699-A | Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |