Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670886 | 1.00 | PTGS2 (0.51) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL15688634 | 1.00 | PTGS2 (0.51) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL15688633 | 1.00 | PTGS2 (0.51) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL2008642 | 1.00 | PTGS2 (0.51) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL2008644 | 1.00 | PTGS2 (0.51) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL6437684 | 0.98 | PTGS2 (0.53) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL6437741 | 0.98 | PTGS2 (0.53) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL6437682 | 0.98 | PTGS2 (0.53) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL15689016 | 0.94 | PTGS2 (0.54) | PTGS2MAPTALDH1A1APPMEN1 | |
| SCHEMBL15689017 | 0.94 | PTGS2 (0.54) | PTGS2MAPTALDH1A1APPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753649-A | Therapeutic agent for osteoporosis and diazepine compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5593988-A | DIAZIPINE DERIVATIVES OF THIOPHENE FOR BONE DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |