Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948513 | 0.72 | JAK3 (0.41) | SRD5A2SMN1; SMN2RAB9AJAK3ALDH1A1 | |
| SCHEMBL9948893 | 0.71 | JAK3 (0.44) | SRD5A2SMN1; SMN2RAB9AJAK3RIPK1 | |
| SCHEMBL22104899 | 0.68 | CYP2D6 (0.51) | SRD5A2SMN1; SMN2RIPK1CYP2D6 | |
| SCHEMBL3084598 | 0.67 | — | — | |
| SCHEMBL24922533 | 0.64 | RAB9A (0.42) | SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL22104901 | 0.63 | CYP2D6 (0.46) | RIPK1CYP2D6 | |
| SCHEMBL9949154 | 0.63 | HTR2A (0.36) | SMN1; SMN2JAK3RIPK1CYP2D6 | |
| SCHEMBL9064028 | 0.63 | — | — | |
| SCHEMBL13896080 | 0.61 | SMN1; SMN2 (0.40) | SRD5A2SMN1; SMN2RAB9AJAK3ALDH1A1 | |
| SCHEMBL24922542 | 0.61 | RAB9A (0.42) | SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |