Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.65 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAD52 | P43351 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | NGFR | P08138 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2285573 | 0.87 | FTO (0.72) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8670977 | 0.87 | FTO (0.63) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8664254 | 0.83 | HEXA (0.69) | MEN1KMT2APOLBMAPTKDM4E | |
| SCHEMBL1901643 | 0.82 | FTO (0.72) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL1893251 | 0.82 | FTO (0.72) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8670304 | 0.82 | CYP2D6 (0.64) | FTOMEN1KMT2APOLBMAPT | |
| SCHEMBL26773419 | 0.82 | FTO (0.76) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL9501837 | 0.81 | FTO (0.82) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8668319 | 0.81 | HEXA (0.52) | FTOMEN1KMT2APOLBMAPT | |
| SCHEMBL12660522 | 0.81 | FTO (0.64) | FTOPABPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789418-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |