Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.64 |
| ▸ | MME | P08473 | 2/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | CPA1 | P15085 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659514 | 1.00 | HRH4 (0.64) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL10722504 | 0.90 | PIN1 (0.64) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL2780518 | 0.89 | PTPN1 (0.58) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL8671488 | 0.86 | HRH4 (0.60) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL3662085 | 0.86 | HRH4 (0.60) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL3662089 | 0.86 | HRH4 (0.60) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL3654490 | 0.84 | MME (0.64) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL8673936 | 0.84 | MME (0.64) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL8669871 | 0.84 | HRH4 (0.58) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL3660841 | 0.83 | MME (0.62) | HRH4MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |