Hexane

Hexane

SCHEMBL8671572

CCCCCC.N.N.O=C1CCC(=O)O1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
CYP1A2 P05177 3/20 0.44
ALDH1A1 P00352 2/20 0.37
SIRT2 Q8IXJ6 1/20 0.37
TP53 P04637 1/20 0.36
THRB P10828 2/20 0.35
FAAH O00519 1/20 0.35
MGLL Q99685 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CDC25A P30304 5/20 0.33
CDC25B P30305 5/20 0.33
CDC25C P30307 4/20 0.33
ALOX5 P09917 2/20 0.33
PRKCA P17252 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexadecane SCHEMBL21433653 0.95 TSHR (0.58) TSHRCYP1A2ALDH1A1SIRT2THRB
SCHEMBL19172083 0.95 TSHR (0.58) TSHRCYP1A2ALDH1A1SIRT2THRB
Decane SCHEMBL21433652 0.95 TSHR (0.58) TSHRCYP1A2ALDH1A1SIRT2THRB
Dodecane SCHEMBL10535874 0.95 TSHR (0.58) TSHRCYP1A2ALDH1A1SIRT2THRB
SCHEMBL28113536 0.86 TSHR (0.50) TSHRCYP1A2ALDH1A1SIRT2TP53
Butane SCHEMBL10624113 0.86 TSHR (0.69) TSHRCYP1A2ALDH1A1TP53
Dodecanol SCHEMBL10346359 0.84 LMNA (0.54) TSHRCYP1A2ALDH1A1SIRT2PRKCA
Butyl Alcohol SCHEMBL10545495 0.83 TSHR (0.50) TSHRCYP1A2ALDH1A1SIRT2TP53
SCHEMBL9866584 0.81 TSHR (0.48) TSHRCYP1A2ALDH1A1GAA
Ammonia Solution, Strong SCHEMBL1484118 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5747352-A Reagents and methods for the rapid and quantitative assay of pharmacological agents BECKMAN INSTRUMENTS, INC. (US) 1998-05-05 US disclosed
EP-0710361-A1 REAGENTS AND METHODS FOR THE RAPID AND QUANTITATIVE ASSAY OF PHARMACOLOGICAL AGENTS BECKMAN INSTRUMENTS, INC. (US) 1996-05-08 EP disclosed
WO-1995032428-A1 REAGENTS AND METHODS FOR THE RAPID AND QUANTITATIVE ASSAY OF PHARMACOLOGICAL AGENTS BECKMAN INSTRUMENTS, INC. (US) 1995-11-30 WO disclosed