Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SPOP | O43791 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673308 | 0.87 | HSD17B10 (0.39) | KDM4EHSD17B10TDP1TSHRALDH1A1 | |
| SCHEMBL8673312 | 0.87 | HSD17B10 (0.39) | KDM4EHSD17B10TDP1TSHRALDH1A1 | |
| SCHEMBL8869474 | 0.86 | KDM4E (0.36) | KDM4EHSD17B10TDP1TSHRSPOP | |
| SCHEMBL8670569 | 0.86 | KDM4E (0.36) | KDM4EHSD17B10TDP1TSHRSPOP | |
| SCHEMBL8675321 | 0.84 | MAPK1 (0.54) | KDM4EHSD17B10TDP1SPOPALDH1A1 | |
| SCHEMBL8869065 | 0.84 | MAPK1 (0.54) | KDM4EHSD17B10TDP1SPOPALDH1A1 | |
| SCHEMBL8673687 | 0.82 | HSD17B10 (0.37) | KDM4EHSD17B10TDP1TSHRALDH1A1 | |
| SCHEMBL8868640 | 0.82 | HSD17B10 (0.37) | KDM4EHSD17B10TDP1TSHRALDH1A1 | |
| SCHEMBL8672280 | 0.82 | KDM4E (0.39) | KDM4EHSD17B10TDP1TSHRALDH1A1 | |
| SCHEMBL8672281 | 0.82 | KDM4E (0.39) | KDM4EHSD17B10TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789584-A | Substituted-pyridinyl cephalosporin antibiotics active against methicillin resistant bacteria | MICROCIDE PHARMACEUTICALS, INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5756493-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5698547-A | 7-(ACYLAMINO)-3-(ARYLTHIO)-3-CEPHEM-4-CARBOXYLIC ACIDS WHICH EXHIBIT ANTIBACTERIAL ACTIVITY AGAINST ORGANISMS RESISTANT TO BETA-LACTAM ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |
| US-5593986-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |