Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | SPOP | O43791 | 3/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675321 | 1.00 | MAPK1 (0.54) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8671192 | 0.93 | MAPK1 (0.54) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8674886 | 0.93 | MAPK1 (0.54) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8672879 | 0.92 | MAPK1 (0.57) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8672882 | 0.92 | MAPK1 (0.57) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8670220 | 0.90 | SPOP (0.42) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8868325 | 0.90 | SPOP (0.42) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8870561 | 0.89 | MAPK1 (0.50) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8675645 | 0.89 | MAPK1 (0.50) | MAPK1TDP1MAPTPOLBPKM | |
| SCHEMBL8673324 | 0.87 | MAPK1 (0.57) | MAPK1TDP1MAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |
| US-5593986-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |