Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12946414 | 0.82 | — | — | |
| SCHEMBL28098351 | 0.80 | TDP1 (0.56) | TDP1HSD17B10ALDH1A1TSHR | |
| SCHEMBL11763114 | 0.78 | TDP1 (0.55) | TDP1HSD17B10ALDH1A1TSHRTHRB | |
| SCHEMBL483550 | 0.78 | — | — | |
| SCHEMBL8190352 | 0.78 | TDP1 (0.55) | TDP1HSD17B10ALDH1A1TSHRMGAM | |
| SCHEMBL15679520 | 0.78 | ALDH1A1 (0.50) | TDP1HSD17B10ALDH1A1TSHRMGAM | |
| SCHEMBL10482008 | 0.77 | HSD17B10 (0.32) | TDP1HSD17B10 | |
| SCHEMBL7912400 | 0.76 | — | — | |
| SCHEMBL12946415 | 0.75 | HSD17B10 (0.41) | TDP1HSD17B10ALDH1A1TSHRMGAM | |
| SCHEMBL14580322 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710150-A | ARGININE VASOPRESSIN ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0716083-A1 | BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |