SCHEMBL8672240

SCHEMBL8672240

C=CCCCCCCCCC1=NCCO1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20752971 1.00 TDP1 (0.38) TDP1USP2ALDH1A1HPGDLMNA
SCHEMBL965784 0.98 TDP1 (0.35) TDP1USP2ALDH1A1HPGDLMNA
SCHEMBL181528 0.85
SCHEMBL10410293 0.84 ADRA2A (0.32)
SCHEMBL9003861 0.84 ADRA2A (0.32)
SCHEMBL27490832 0.84 ADRA2A (0.32)
SCHEMBL471908 0.84 ADRA2A (0.32)
SCHEMBL381129 0.84 ADRA2A (0.32)
SCHEMBL27966218 0.84 ADRA2A (0.32)
SCHEMBL27966021 0.84 ADRA2A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847145-A Alkylalkoxysilyl-1,3-oxazolines, a method of production and use DEGUSSA AKTIENGESELLSCHAFT (DE) 1998-12-08 US claimed
JP-9227582-A None JP disclosed
US-12247168-B2 Curable photochromic compositions including an oxazoline functional material TRANSITIONS OPTICAL, LTD. (IE) 2025-03-11 US disclosed
US-20230059569-A1 Curable Photochromic Compositions Including an Oxazoline Functional Material TRANSITIONS OPTICAL, LTD. (IE) 2023-02-23 US disclosed
EP-4081595-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING AN OXAZOLINE FUNCTIONAL MATERIAL Transitions Optical, Ltd. (IE) 2022-11-02 EP disclosed
CN-114901748-A Curable photochromic compositions comprising oxazoline-functional materials 光学转变有限公司 2022-08-12 CN disclosed
WO-2021129940-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING AN OXAZOLINE FUNCTIONAL MATERIAL TRANSITIONS OPTICAL, LTD. (IE) 2021-07-01 WO disclosed
US-5847145-A Alkylalkoxysilyl-1,3-oxazolines, a method of production and use DEGUSSA AKTIENGESELLSCHAFT (DE) 1998-12-08 US disclosed
JP-H09227582-A ALKYLALKOXYSILYL-1,3-OXAZOLINE, ITS PRODUCTION AND SILICATE-BASED SURFACE MODIFIED BY USING THE SAME DEGUSSA AG 1997-09-02 JP disclosed
EP-0791598-A2 Alkylalkoxysilyl-1,3-oxazoline, process for its preparation and use Degussa Aktiengesellschaft (DE) 1997-08-27 EP disclosed