Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 9/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550788 | 0.88 | RPS6KA5 (0.37) | ALDH1A1SMN1; SMN2TDP1METRPS6KA5 | |
| SCHEMBL8668305 | 0.85 | MEN1 (0.34) | TDP1 | |
| SCHEMBL8548824 | 0.85 | TDP1 (0.35) | TDP1METRPS6KA5 | |
| SCHEMBL8668983 | 0.85 | MEN1 (0.36) | ALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL8553963 | 0.85 | TDP1 (0.35) | TDP1METRPS6KA5 | |
| SCHEMBL8672353 | 0.82 | TDP1 (0.40) | TLR8ALDH1A1SMN1; SMN2TDP1MET | |
| SCHEMBL8548822 | 0.81 | TDP1 (0.35) | TDP1METRPS6KA5CYP3A4 | |
| SCHEMBL8550786 | 0.81 | RPS6KA5 (0.36) | TDP1METRPS6KA5CYP3A4 | |
| SCHEMBL8553961 | 0.80 | TDP1 (0.34) | TDP1METRPS6KA5CYP3A4 | |
| SCHEMBL8672641 | 0.78 | TLR8 (0.38) | TLR8ALDH1A1SMN1; SMN2TDP1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |