Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 8/20 | 0.34 |
| ▸ | NCF1 | P14598 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672646 | 0.88 | TLR8 (0.39) | RPS6KA5TDP1METMAPK10ALDH1A1 | |
| SCHEMBL8553963 | 0.88 | TDP1 (0.35) | RPS6KA5TDP1MET | |
| SCHEMBL8548824 | 0.86 | TDP1 (0.35) | RPS6KA5TDP1MET | |
| SCHEMBL8550417 | 0.86 | RXRA (0.34) | NCF1RXRAPPARGNR1H3ALDH1A1 | |
| SCHEMBL8553022 | 0.85 | KDM4E (0.40) | KDM4EHSD17B10NCF1MAPTALDH1A1 | |
| SCHEMBL7923747 | 0.84 | KDM4E (0.41) | KDM4EHSD17B10NCF1MAPTALDH1A1 | |
| SCHEMBL8547167 | 0.82 | TDP1 (0.41) | RPS6KA5TDP1KDM4EHSD17B10MET | |
| SCHEMBL8550786 | 0.82 | RPS6KA5 (0.36) | RPS6KA5TDP1KDM4EMETMAPT | |
| SCHEMBL8548822 | 0.80 | TDP1 (0.35) | RPS6KA5TDP1METPRKACARPS6KB1 | |
| SCHEMBL8553961 | 0.80 | TDP1 (0.34) | RPS6KA5TDP1METCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |