SCHEMBL8672999

SCHEMBL8672999

C=NC(=C)C(=O)Oc1ccc(C(=O)OCC)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.52
ACR P10323 1/20 0.52
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
STS P08842 1/20 0.49
CYP1A2 P05177 2/20 0.49
LMNA P02545 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAOA P21397 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SLC22A2 O15244 1/20 0.47
TMPRSS2 O15393 1/20 0.47
F2 P00734 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1888095 0.83 ELANE (0.58) PRSS1ACRCA12CA1CA2
SCHEMBL10344282 0.79 PRSS1 (0.69) PRSS1ACRCA12CA1CA2
SCHEMBL1412698 0.78 CA12 (0.49) PRSS1ACRCA12CA1CA2
SCHEMBL1721471 0.77 CA1 (0.63) PRSS1ACRCA12CA1CA2
SCHEMBL1176935 0.76 CA12 (0.61) PRSS1ACRCA12CA1CA2
SCHEMBL11839486 0.76 CA12 (0.61) PRSS1ACRCA12CA1CA2
SCHEMBL1061004 0.75 THRB (0.57) PRSS1ACRCA12CA1CA2
SCHEMBL6693904 0.75 ESR1 (0.56) PRSS1ACRCA12CA1CA2
SCHEMBL87450 0.75 CA1 (0.83) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL11839482 0.74 PRSS1 (0.60) PRSS1ACRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5833880-A MIXTURE POLYMERIZABLE BY FREE RADICAL OR IONIC POLYMERIZATION BASF AKTIENGESELLSCHAFT (DE) 1998-11-10 US disclosed