Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | PNP | P00491 | 4/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 10/20 | 0.50 |
| ▸ | DBH | P09172 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021120 | 0.87 | PNP (0.70) | MEN1LMNAKMT2AADORA2AADORA1 | |
| SCHEMBL9393674 | 0.83 | BRD4 (0.43) | MEN1LMNAKMT2AADORA2AADORA1 | |
| SCHEMBL23388239 | 0.79 | ADORA2A (0.67) | MEN1LMNAKMT2AADORA2AADORA1 | |
| SCHEMBL25511872 | 0.78 | MEN1 (0.59) | MEN1LMNAKMT2AADORA2AADORA1 | |
| SCHEMBL29853379 | 0.75 | MEN1 (0.58) | MEN1LMNAKMT2AADORA2AADORA1 | |
| SCHEMBL946430 | 0.75 | MEN1 (0.58) | MEN1LMNAKMT2AADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL7813292 | 0.73 | DHFR (0.56) | MEN1LMNAKMT2AADORA2AADORA1 | |
| SCHEMBL7743914 | 0.71 | SLC29A1 (0.41) | LMNASLC29A1 | |
| SCHEMBL25511867 | 0.71 | MEN1 (0.51) | MEN1LMNAKMT2AADORA2AADORA1 | |
| SCHEMBL1262622 | 0.71 | PNP (0.79) | MEN1LMNAKMT2APNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |