SCHEMBL8673162

SCHEMBL8673162

CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)O

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 15/20 0.70
OPRM1 P35372 8/20 0.70
OPRK1 P41145 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8673006 1.00 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL9724057 1.00 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL29689553 0.89 OPRD1 (0.66) OPRD1OPRM1OPRK1
SCHEMBL29394698 0.89 OPRD1 (0.76) OPRD1OPRM1OPRK1
SCHEMBL29973200 0.89 OPRD1 (0.76) OPRD1OPRM1OPRK1
SCHEMBL1374934 0.88 OPRD1 (0.59) OPRD1OPRM1OPRK1
SCHEMBL4409294 0.87 SLC7A5 (0.62) OPRD1OPRM1OPRK1
SCHEMBL6047681 0.87 SLC7A5 (0.62) OPRD1OPRM1OPRK1
SCHEMBL4407092 0.87 SLC7A5 (0.62) OPRD1OPRM1OPRK1
SCHEMBL7588269 0.87 OPRD1 (0.59) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597838-B1 VACCINE COMPOSITIONS NORTH AMERICAN VACCINE INC (CA) 1998-12-02 EP claimed
EP-0549617-B1 IMPROVED VACCINE COMPOSITIONS NORTH AMERICAN VACCINE INC (CA) 1996-03-27 EP claimed
CN-1060408-A Improved vaccine combination NORTH AMERICAN VACCINE INC (CA) 1992-04-22 CN claimed
CN-1056816-A The vaccine combination of improvement NORTH AMERICAN VACCINES INC (CA) 1991-12-11 CN claimed