Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241276 | 0.83 | TSHR (0.39) | TSHRABCC4MAPTALDH1A1 | |
| SCHEMBL87334 | 0.75 | TSHR (0.43) | TSHRALDH1A1 | |
| SCHEMBL6430768 | 0.73 | — | — | |
| SCHEMBL207948 | 0.73 | — | — | |
| SCHEMBL10696540 | 0.71 | — | — | |
| SCHEMBL8670878 | 0.71 | — | — | |
| SCHEMBL595267 | 0.69 | TSHR (0.43) | TSHRALDH1A1 | |
| SCHEMBL28850176 | 0.69 | ALDH1A1 (0.30) | ABCC4MAPTALDH1A1 | |
| SCHEMBL16922278 | 0.69 | — | — | |
| SCHEMBL176308 | 0.69 | TSHR (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |