Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179529 | 0.92 | MEN1 (0.53) | KDM4EMEN1KMT2ADHODHPARP1 | |
| SCHEMBL8673322 | 0.85 | KDM4E (0.54) | KDM4EMEN1KMT2ADHODHPARP1 | |
| SCHEMBL8671753 | 0.83 | CYP1A2 (0.53) | KDM4EMEN1KMT2ADHODHPARP1 | |
| SCHEMBL660585 | 0.83 | KDM4E (0.44) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3970182 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL7852029 | 0.82 | MEN1 (0.51) | KDM4EMEN1KMT2ADHODHPARP1 | |
| SCHEMBL8671748 | 0.82 | MEN1 (0.51) | KDM4EMEN1KMT2ADHODHPARP1 | |
| SCHEMBL28014894 | 0.82 | NCF1 (0.53) | KDM4EMEN1KMT2ADHODHPARP1 | |
| SCHEMBL8673320 | 0.82 | KDM4E (0.54) | KDM4EMEN1KMT2ADHODHPARP1 | |
| SCHEMBL9187156 | 0.81 | KDM4E (0.64) | KDM4EMEN1KMT2APARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817674-A | ANTIOTENSIN II RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1998-10-06 | — | — | US | disclosed |