Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.92 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.92 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | SLC25A21 | Q9BQT8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diallyl Sulfide SCHEMBL8673376 | 1.00 | ALOX5 (0.92) | ALOX5SMN1; SMN2TRPA1ALDH1A1CYP3A4 | |
| Diallyl Sulfide SCHEMBL4346718 | 0.96 | — | — | |
| Diallyl Sulfide SCHEMBL45800 | 0.96 | — | — | |
| Diallyl Sulfide SCHEMBL14764035 | 0.96 | ALOX5 (1.00) | ALOX5SMN1; SMN2TRPA1ALDH1A1CYP3A4 | |
| Diallyl Sulfide SCHEMBL4560172 | 0.92 | — | — | |
| Diallyl Sulfide SCHEMBL7130288 | 0.92 | — | — | |
| Diallyl Sulfide SCHEMBL11665328 | 0.92 | — | — | |
| Diallyl Sulfide SCHEMBL9280151 | 0.92 | — | — | |
| Diallyl Sulfide SCHEMBL21385126 | 0.92 | ALOX5 (0.92) | ALOX5SMN1; SMN2TRPA1ALDH1A1CYP3A4 | |
| Diallyl Sulfide SCHEMBL7573176 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601909-B1 | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof | ZAIDAN HOJIN BISEIBUTSU (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5618795-A | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5488038-A | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0601909-A2 | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-06-15 | — | — | EP | disclosed |