Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339013 | 0.93 | AVPR2 (0.38) | ABL1FYNSRCPTK6MEN1 | |
| SCHEMBL7339138 | 0.85 | AVPR2 (0.43) | ABL1FYNSRCPTK6KMT2A | |
| SCHEMBL7340438 | 0.82 | ABL1 (0.38) | ABL1FYNSRCPTK6KMT2A | |
| Hydrochloric Acid SCHEMBL7336979 | 0.82 | AVPR2 (0.40) | MEN1KMT2APTK2AVPR2AVPR1A | |
| SCHEMBL7337083 | 0.80 | AVPR2 (0.43) | ABL1FYNSRCPTK6AVPR2 | |
| SCHEMBL7338676 | 0.80 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BADRA1DADRA1A | |
| SCHEMBL7342434 | 0.80 | AVPR2 (0.42) | KMT2AAVPR2AVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7780856 | 0.80 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BADRA1DADRA1A | |
| SCHEMBL7338448 | 0.79 | AVPR2 (0.37) | MEN1KMT2AAVPR2AVPR1AAVPR1B | |
| SCHEMBL7340542 | 0.79 | AVPR2 (0.37) | KMT2AAVPR2AVPR1AAVPR1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |