Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673364 | 0.86 | ALDH1A1 (0.36) | TDP1ALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27448383 | 0.86 | ALDH1A1 (0.33) | ALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8674878 | 0.85 | TACR1 (0.35) | ACHELMNATSHRALOX12CYP11B1 | |
| Hydrochloric Acid SCHEMBL7940146 | 0.84 | ALDH1A1 (0.32) | ALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8673021 | 0.83 | HTR2C (0.34) | PRCPCYP11B2MEN1KMT2A | |
| SCHEMBL8676698 | 0.82 | TSHR (0.36) | NPC1RAB9ALMNATSHRALDH1A1 | |
| SCHEMBL27618424 | 0.79 | EDNRB (0.33) | NPC1RAB9ANFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL1983257 | 0.78 | PRCP (0.33) | NPC1RAB9ANFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL6287243 | 0.78 | CYP11B1 (0.32) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL7031934 | 0.78 | NPC1 (0.31) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747621-A | CATALYTIC ADDITION POLYMERIZATION | MONTELL TECHNOLOGY COMPANY BV (NL) | 1998-05-05 | — | — | US | disclosed |
| CN-1147822-A | Reactor blend polypropylene, process for the preparation thereof and process for preparing metallocene ligands | MONTELL TECHNOLOGY COMPANY BV (NL) | 1997-04-16 | — | — | CN | disclosed |