SCHEMBL867390

SCHEMBL867390

CC(C)OC(=O)c1cc(N)cc(N)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.62
CA1 P00915 6/20 0.62
CA2 P00918 6/20 0.62
CA7 P43166 6/20 0.62
CA9 Q16790 6/20 0.62
CA14 Q9ULX7 6/20 0.62
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
NPC1 O15118 4/20 0.45
RAB9A P51151 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
PTPN11 Q06124 2/20 0.43
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 1/20 0.42
ELANE P08246 1/20 0.42
ALDH1A1 P00352 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588666 0.96 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL11651683 0.87 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL15054077 0.86 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL16606258 0.84 CA12 (0.75) CA12CA1CA2CA7CA9
SCHEMBL8715898 0.82 MAPT (0.51) CA12CA1CA2CA7CA9
SCHEMBL8930000 0.81 ELANE (0.56) CA12CA1CA2CA7CA9
SCHEMBL27638597 0.81 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL5924235 0.80 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL9064984 0.80 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL3320116 0.79 CA12 (0.68) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115318113-A Nanofiltration membrane and preparation method and application thereof 清华大学 2022-11-11 CN claimed
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
CN-101040028-B Photocrosslinkable materials ROLIC AG 2012-03-28 CN claimed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US claimed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 US claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
CN-100551902-C light active material ROLIC AG (CH) 2009-10-21 CN claimed
CN-100551952-C Photoactive polymer ROLIC AG (CH) 2009-10-21 CN claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
CN-101040028-A Photocrosslinkable materials ROLIC AG (CH) 2007-09-19 CN claimed
US-20030226215-A1 Enzymatic method for textile dying NOVOZYMES NORTH AMERICA, INC. (US) 2003-12-11 US claimed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 EP claimed
WO-2003016615-A1 SINGLE BATH PROCESS FOR BLEACHING AND DYEING TEXTILES NOVOZYMES NORTH AMERICA, INC. (US) 2003-02-27 WO claimed
EP-1266068-A1 ENZYMATIC METHOD FOR TEXTILE DYEING Novozymes North America, Inc. (US) 2002-12-18 EP claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO claimed
EP-1229066-A1 Photoactive polymer Rolic AG (CH) 2002-08-07 EP claimed
US-20010037532-A1 Enzymatic method for textile dyeing NOVOZYMES A/S (DK) 2001-11-08 US claimed
US-6296672-B1 PEROXIDASE, OXIDOREDUCTASE, LACCASE NOVOZYMES A/S PATENTS (DK) 2001-10-02 US claimed
WO-2001044563-A1 ENZYMATIC METHOD FOR TEXTILE DYEING NOVOZYMES NORTH AMERICA, INC. (US) 2001-06-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 CA12 2386/4885CA1 882/4885CA2 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.