Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA7 | P43166 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251730 | 0.97 | CA2 (0.43) | CA2CA1CA7CA9CA12 | |
| SCHEMBL27494520 | 0.97 | CA2 (0.43) | CA2CA1CA7CA9CA12 | |
| SCHEMBL2138768 | 0.97 | CA2 (0.43) | CA2CA1CA7CA9CA12 | |
| SCHEMBL27638880 | 0.91 | CA2 (0.39) | CA2CA1CA7CA9CA12 | |
| SCHEMBL27879858 | 0.89 | CA2 (0.37) | CA2CA1CA7CA9CA12 | |
| SCHEMBL9407196 | 0.89 | CA1 (0.42) | CA2CA1CA7CA9CA12 | |
| SCHEMBL542567 | 0.83 | NPSR1 (0.35) | CA2CA1CA7CA9CA12 | |
| SCHEMBL182827 | 0.83 | MAPT (0.46) | ALDH1A1MAPK1L3MBTL1TSHRTP53 | |
| SCHEMBL159256 | 0.83 | KDM4E (0.42) | CA2CA1CA7CA9CA12 | |
| SCHEMBL316596 | 0.83 | CA12 (0.36) | CA2CA1CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15668 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307569-A | 2-Aryl-4-boron heterocyclic compound, and stereoselective preparation method and application thereof | 武汉大学 | 2024-07-09 | — | — | CN | claimed |
| CN-116332908-B | SHP2 allosteric inhibitor and preparation method and application thereof | 杭州医学院 | 2024-07-02 | — | — | CN | claimed |
| CN-118265702-A | Microbiocidal isonicotinamide derivatives | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | claimed |
| US-12020872-B2 | Stilbene and fused stilbene derivatives as solar cell dyes | Ambient Photonics, Inc. (US) | 2024-06-25 | — | — | US | claimed |
| CN-118239868-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118221922-A | Cobalt-based catalyst composition and method for preparing polyester by catalyzing copolymerization of epoxy and carbon monoxide | 中山大学 | 2024-06-21 | — | — | CN | claimed |
| US-20240199623-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS CFTR MODULATORS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2024-06-20 | — | — | US | claimed |
| CN-118206551-A | Quinoline compounds, their preparation and their use as antimalarial agents | 美国卫生和人力服务部 | 2024-06-18 | — | — | CN | claimed |
| US-20240182471-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-06-06 | — | — | US | claimed |
| CN-114891019-B | Continuous flow preparation method of vinyl thioether compound | 复旦大学 | 2024-06-04 | — | — | CN | claimed |
| US-4011262-A | 13,14-Dihydro-15-substituted-ω-pentanorprostaglandins of the two series | PFIZER INC. (US) | 1977-03-08 | — | — | US | claimed |
| US-3984424-A | MEDICAMENTS | PFIZER INC. (US) | 1976-10-05 | — | — | US | claimed |
| US-3981716-A | CORN, WEEDS | STAUFFER CHEMICAL COMPANY (US) | 1976-09-21 | — | — | US | claimed |
| US-3974213-A | 13,14-Dihydro-15-substituted-ω-pentanorprostaglandins | PFIZER INC. (US) | 1976-08-10 | — | — | US | claimed |
| US-3968214-A | 5-Methylthio-pyrimidine vasodilators | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-07-06 | — | — | US | claimed |
| US-3963756-A | HYDROXYLASE ENZYME INHIBITORS, HYPOTENSIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1976-06-15 | — | — | US | claimed |
| US-3950538-A | Anti-inflammatory methods utilizing certain thioureas | THE DOW CHEMICAL COMPANY (US) | 1976-04-13 | — | — | US | claimed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | claimed |
| US-3932465-A | ANTIBIOTIC | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | claimed |
| US-3932389-A | ANTIULCER AGENTS | PFIZER INC. (US) | 1976-01-13 | — | — | US | claimed |