Hydroxyamine

Hydroxyamine

SCHEMBL8674115

CC1=CC(=O)CC(C)(C)C1.NO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MAPT P10636 5/20 0.44
HPGD P15428 3/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.43
GAA P10253 3/20 0.42
TSHR P16473 2/20 0.42
GLA P06280 1/20 0.42
ALOX15 P16050 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
LMNA P02545 3/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
PKM P14618 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PAX8 Q06710 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL27826285 0.93 ALDH1A1 (0.48) ALDH1A1MAPTHPGDKMT2AMEN1
Methyl Alcohol SCHEMBL9328801 0.93 ALDH1A1 (0.48) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL22522 0.93 ALDH1A1 (0.52) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL7102666 0.93 ALDH1A1 (0.52) ALDH1A1MAPTHPGDKMT2AMEN1
Urea SCHEMBL28209428 0.92 MAPT (0.45) ALDH1A1MAPTHPGDKMT2AMEN1
Ammonia Solution, Strong SCHEMBL1984334 0.91 ALDH1A1 (0.50) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL271129 0.91 ALDH1A1 (0.50) ALDH1A1MAPTHPGDKMT2AMEN1
Water SCHEMBL28863261 0.91 ALDH1A1 (0.50) ALDH1A1MAPTHPGDKMT2AMEN1
Ammonia Solution, Strong SCHEMBL10613596 0.91 ALDH1A1 (0.50) ALDH1A1MAPTHPGDKMT2AMEN1
Water SCHEMBL9637163 0.91 ALDH1A1 (0.50) ALDH1A1MAPTHPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294787-A1 METHOD FOR MANUFACTURE OF ISOPHORONEDIAMINE BASF SE (DE) 2023-12-27 EP claimed
CN-116867764-A Method for producing isophorone diamine 巴斯夫欧洲公司 2023-10-10 CN claimed
WO-2022175153-A1 METHOD FOR MANUFACTURE OF ISOPHORONEDIAMINE BASF SE (DE) 2022-08-25 WO claimed
EP-4294787-A1 METHOD FOR MANUFACTURE OF ISOPHORONEDIAMINE BASF SE (DE) 2023-12-27 EP disclosed
CN-116867764-A Method for producing isophorone diamine 巴斯夫欧洲公司 2023-10-10 CN disclosed
CN-116867764-A Method for producing isophorone diamine 巴斯夫欧洲公司 2023-10-10 CN disclosed
WO-2022175153-A1 METHOD FOR MANUFACTURE OF ISOPHORONEDIAMINE BASF SE (DE) 2022-08-25 WO disclosed
US-10392469-B2 Epoxy resin compositions for production of storage-stable composites EVONIK DEGUSSA GMBH (DE) 2019-08-27 US disclosed
US-10280252-B2 Latent epoxy resin formulations for liquid impregnation processes for production of fibre composite materials EVONIK DEGUSSA GMBH (DE) 2019-05-07 US disclosed
US-10221277-B2 Epoxy resin composition comprising 2-(3-(aminomethyl)-3,5,5-trimethylcyclohexyl)propane-1,3-diamine (AM-CPDA) as hardener EVONIK DEGUSSA GMBH (DE) 2019-03-05 US disclosed
US-10155840-B2 Latent epoxy resin formulations for liquid impregnation processes for production of fibre-reinforced composites EVONIK DEGUSSA GMBH (DE) 2018-12-18 US disclosed
US-20170166688-A1 LATENT EPOXY RESIN FORMULATIONS FOR LIQUID IMPREGNATION PROCESSES FOR PRODUCTION OF FIBRE-REINFORCED COMPOSITES EVONIK DEGUSSA GMBH (DE) 2017-06-15 US disclosed
US-20170166687-A1 EPOXY RESIN COMPOSITIONS FOR PRODUCTION OF STORAGE-STABLE COMPOSITES EVONIK DEGUSSA GMBH (DE) 2017-06-15 US disclosed
EP-3162791-A1 IMPROVED PROCESS FOR THE PREPARATION OF ISOPHORONE AMINO ALCOHOL (IPAA) Evonik Degussa GmbH (DE) 2017-05-03 EP disclosed
EP-3162790-A1 METHOD FOR PRODUCING ISOPHORONE AMINO ALCOHOL (IPAA) Evonik Degussa GmbH (DE) 2017-05-03 EP disclosed
US-5852217-A Process for the production of primary and/or secondary amines from oxo compounds DEGUSSA AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
US-5679860-A Process for the production of 3-aminoethyl-3,5,5-trimethylcyclohexyl amine DEGUSSA AKTIENGESELLSCHAFT (DE) 1997-10-21 US disclosed
US-5283366-A REDUCTIVE AMINATION OF 1,3,3-TRIMETHYL-5-OXOCYCLOHEXANE CARBO-NITRILE WITH AMMONIA AND HYDROGEN IN THE PRESENCE OF RANEY NICKEL OR COBALT WITH COCATALYSTS OF SALTS OF NICKEL OR COBALT; HEATING, PRESSURIZATION DEGUSSA AG (DE) 1994-02-01 US disclosed
US-5166444-A Chemical intermediates as hardeners for epoxy resins formed by hydrogenation in the presence of a nickel catalyst DEGUSSA AG (DE) 1992-11-24 US disclosed
US-5166396-A Chemical intermediates as hardeners for epoxy resins DEGUSSA AG (DE) 1992-11-24 US disclosed