Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232787 | 0.79 | ACHE (0.47) | ACHEHTR2AHTR2CALDH1A1MEN1 | |
| SCHEMBL5232775 | 0.79 | ACHE (0.47) | ACHEHTR2AHTR2CALDH1A1MEN1 | |
| SCHEMBL5232781 | 0.79 | ACHE (0.47) | ACHEHTR2AHTR2CALDH1A1MEN1 | |
| SCHEMBL10041963 | 0.77 | HPGD (0.49) | ACHEHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL3370114 | 0.77 | HPGD (0.49) | ACHEHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL3370115 | 0.77 | HPGD (0.49) | ACHEHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL30363500 | 0.77 | HPGD (0.49) | ACHEHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL15395845 | 0.76 | ACHE (0.47) | ACHEHTR2AHTR2CPARP1PARP10 | |
| SCHEMBL14625576 | 0.71 | HTR2C (0.64) | ACHEHTR2AHTR2CSRD5A1HTR1D | |
| SCHEMBL25295761 | 0.69 | HTT (0.49) | ACHEPARP1PARP10SRD5A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849945-A | Aminotetralone derivatives and preparation process thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0811603-A1 | AMINOTETRALONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |