SCHEMBL8674322

SCHEMBL8674322

CSc1c(N)cccc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.48
TSHR P16473 5/20 0.48
PIK3CA P42336 1/20 0.48
ALDH1A1 P00352 5/20 0.43
TDP1 Q9NUW8 4/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALOX15 P16050 2/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CD44 P16070 1/20 0.42
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
KEAP1 Q14145 1/20 0.36
ADRA2B P18089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8672406 0.97 CYP3A4 (0.46) CYP3A4TSHRPIK3CAALDH1A1TDP1
Hydrochloric Acid SCHEMBL8678950 0.92 CYP3A4 (0.50) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL9180527 0.85 MEN1 (0.42) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL30966305 0.85 CYP3A4 (0.40) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL3781780 0.83 ALDH1A1 (0.52) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL6365906 0.83 CYP3A4 (0.39) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL29701738 0.83 CYP3A4 (0.39) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL3791406 0.81 ALDH1A1 (0.56) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL3792751 0.79 TSHR (0.36) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL3787567 0.78 ALDH1A1 (0.56) CYP3A4TSHRPIK3CAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107636039-B Curing agent for thermosetting epoxy resins and method for producing insulation systems for electronic engineering 亨斯迈先进材料许可(瑞士)有限公司 2020-11-24 CN claimed
EP-2950773-B1 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE OREAL (FR) 2019-03-13 EP claimed
CN-107636039-A Curing agent and the method for preparing insulation system for electronic engineering for thermosetting epoxy resin 亨斯迈先进材料许可(瑞士)有限公司 2018-01-26 CN claimed
EP-0586660-B1 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR OREAL (FR) 1997-01-29 EP claimed
EP-0586660-A1 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR. OREAL (FR) 1994-03-16 EP claimed
WO-1993018739-A1 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR L'OREAL (FR) 1993-09-30 WO claimed
CN-118234975-A Polyurethane tapes with improved hydrolysis resistance 盖茨公司 2024-06-21 CN disclosed
CN-118043209-A Tire with tread comprising reinforcing elements 米其林集团总公司 2024-05-14 CN disclosed
CN-117980365-A Silicone-modified polyurethane compositions 信越化学工业株式会社 2024-05-03 CN disclosed
CN-117903671-A Silicone-modified polyurethane resin coating agent composition 信越化学工业株式会社 2024-04-19 CN disclosed
CN-112512747-B Polishing pad and method for producing polished product 富士纺控股株式会社 2024-04-05 CN disclosed
CN-117140344-A polishing pad 霓达杜邦股份有限公司 2023-12-01 CN disclosed
CN-117120213-A Polishing pad and method for producing polished product 富士纺控股株式会社 2023-11-24 CN disclosed
EP-0586660-A1 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR. OREAL (FR) 1994-03-16 EP disclosed
WO-1993018739-A1 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR L'OREAL (FR) 1993-09-30 WO disclosed
EP-0193872-B1 DI(ALKYLTHIO) DIAMINE CHAIN EXTENDERS FOR POLYURETHANE ELASTOMERS ETHYL CORPORATION (US) 1993-03-31 EP disclosed
EP-0289870-A2 Epoxy resin compositions ETHYL CORPORATION (US) 1988-11-09 EP disclosed
US-4757119-A Diamine curing agent ETHYL CORPORATION (US) 1988-07-12 US disclosed
EP-0193872-A2 Di(alkylthio) diamine chain extenders for polyurethane elastomers ETHYL CORPORATION (US) 1986-09-10 EP disclosed
US-4595742-A Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine ETHYL CORPORATION (US) 1986-06-17 US disclosed