Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GABRP | O00591 | 7/20 | 0.39 |
| ▸ | GABRD | O14764 | 7/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.39 |
| ▸ | GABRE | P78334 | 7/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677466 | 0.77 | PTPN5 (0.39) | PTPN5ALDH1A1KDM4EPKMHPGD | |
| SCHEMBL8671708 | 0.77 | PTPN5 (0.39) | PTPN5ALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL8673787 | 0.74 | ALDH1A1 (0.39) | PTPN5ALDH1A1NOS3NOS2KDM4E | |
| SCHEMBL13871750 | 0.73 | PTPN5 (0.47) | PTPN5ALDH1A1NOS3NOS2KDM4E | |
| SCHEMBL8672164 | 0.72 | ALDH1A1 (0.41) | PTPN5ALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL3277186 | 0.72 | SLC6A2 (0.50) | ALDH1A1NOS3NOS2KDM4EPKM | |
| SCHEMBL8675667 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL27202379 | 0.72 | ALDH1A1 (0.57) | PTPN5ALDH1A1NOS3NOS2KDM4E | |
| SCHEMBL8671775 | 0.71 | AR (0.39) | PTPN5ALDH1A1GABRA2GABRB2KDM4E | |
| SCHEMBL24118128 | 0.70 | PTPN5 (0.48) | PTPN5ALDH1A1NOS3NOS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586660-B1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR | OREAL (FR) | 1997-01-29 | — | — | EP | claimed |
| EP-0586660-A1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR. | OREAL (FR) | 1994-03-16 | — | — | EP | claimed |
| WO-1993018739-A1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR | L'OREAL (FR) | 1993-09-30 | — | — | WO | claimed |
| US-5710311-A | 2-sulphured metaphenylenediamines for dyeing hair | L'OREAL (FR) | 1998-01-20 | — | — | US | disclosed |
| EP-0586660-B1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR | OREAL (FR) | 1997-01-29 | — | — | EP | disclosed |
| US-5505741-A | DYEING HAIR BY OXIDATION, RINSING, WASHING WITH SHAMPOO, RINSING AND DRYING | L'OREAL (FR) | 1996-04-09 | — | — | US | disclosed |
| EP-0586660-A1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR. | OREAL (FR) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993018739-A1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR | L'OREAL (FR) | 1993-09-30 | — | — | WO | disclosed |
| US-4327204-A | Process for producing polyurethane elastomer by mixing a hardener composition with an isocyanate composition | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-04-27 | — | — | US | disclosed |