Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | SQLE | Q14534 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445572 | 1.00 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL8666552 | 1.00 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL5915230 | 1.00 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL8668611 | 1.00 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL8672525 | 1.00 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL11685517 | 0.97 | LMNA (0.40) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL9325398 | 0.96 | SMN1; SMN2 (0.39) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL526694 | 0.94 | LMNA (0.38) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL1068156 | 0.94 | LMNA (0.38) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL11019429 | 0.94 | LMNA (0.38) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0686151-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-12-13 | — | — | EP | disclosed |