Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444775 | 0.95 | ALOX15 (0.39) | ALOX15CYP3A4EP300HIF1ACREBBP | |
| SCHEMBL8674651 | 0.93 | ALOX15 (0.38) | ALOX15CYP3A4EP300HIF1ACREBBP | |
| SCHEMBL3677682 | 0.80 | ALOX15 (0.39) | ALOX15CYP3A4ACHEHSD11B1CYP19A1 | |
| SCHEMBL3677681 | 0.80 | ALOX15 (0.39) | ALOX15CYP3A4ACHEHSD11B1CYP19A1 | |
| SCHEMBL4050750 | 0.75 | EP300 (0.35) | ALOX15CYP3A4EP300HIF1ACREBBP | |
| SCHEMBL12918345 | 0.74 | ALOX15 (0.40) | ALOX15EP300HIF1ACREBBPHSD11B1 | |
| SCHEMBL3670483 | 0.74 | FNTA (0.38) | ALOX15CYP3A4CYP19A1F10 | |
| SCHEMBL3670481 | 0.74 | FNTA (0.38) | ALOX15CYP3A4CYP19A1F10 | |
| SCHEMBL3670501 | 0.74 | F10 (0.36) | ALOX15CYP3A4CYP19A1F10 | |
| SCHEMBL3670498 | 0.74 | F10 (0.36) | ALOX15CYP3A4CYP19A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783602-A | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |