Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444773 | 0.95 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10NLRP3CHRM1 | |
| SCHEMBL8444777 | 0.95 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10NLRP3CHRM1 | |
| SCHEMBL8674653 | 0.93 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10NLRP3 | |
| SCHEMBL8674650 | 0.93 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10NLRP3 | |
| SCHEMBL2997498 | 0.93 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10NLRP3 | |
| SCHEMBL15615426 | 0.92 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10NLRP3CHRM1 | |
| SCHEMBL24912279 | 0.90 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10NLRP3CHRM1 | |
| SCHEMBL17550206 | 0.90 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10NLRP3CHRM1 | |
| SCHEMBL23785663 | 0.87 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10NLRP3CHRM1 | |
| SCHEMBL21019789 | 0.86 | CHRM1 (0.33) | ALDH1A1LMNAHSD17B10NLRP3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783602-A | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |