Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677030 | 0.88 | ABCB1 (0.56) | PTGER1MRGPRX4CTSVCTSLABCB1 | |
| SCHEMBL8677039 | 0.84 | MRGPRX4 (0.64) | PTGER1MRGPRX4 | |
| SCHEMBL8677356 | 0.81 | PTGER1 (0.59) | PTGER1MRGPRX4CTSVCTSLABCB1 | |
| SCHEMBL8321719 | 0.81 | MRGPRX4 (0.65) | PTGER1MRGPRX4 | |
| SCHEMBL2313792 | 0.81 | APEX1 (0.53) | MRGPRX4KDM4EGAA | |
| SCHEMBL8677569 | 0.80 | MRGPRX4 (0.62) | PTGER1MRGPRX4 | |
| SCHEMBL8675284 | 0.77 | PTGER1 (0.58) | PTGER1MRGPRX4CTSVCTSLKDM4E | |
| SCHEMBL8409624 | 0.76 | MRGPRX4 (0.66) | PTGER1MRGPRX4 | |
| SCHEMBL8321739 | 0.76 | MRGPRX4 (0.66) | PTGER1MRGPRX4 | |
| SCHEMBL8675286 | 0.76 | PTGER1 (0.54) | PTGER1MRGPRX4CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |