Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674677 | 0.89 | PTGER1 (0.54) | PTGER1MRGPRX4CTSVCTSLKMT2A | |
| SCHEMBL487486 | 0.81 | PTGER1 (0.75) | PTGER1MRGPRX4CYP2C9KMT2AKDM4E | |
| SCHEMBL8675272 | 0.77 | PTGER1 (0.55) | PTGER1MRGPRX4CTSVCTSLKDM4E | |
| SCHEMBL8675286 | 0.77 | PTGER1 (0.54) | PTGER1MRGPRX4CTSVCTSLCYP2C9 | |
| SCHEMBL9789583 | 0.76 | PTGER1 (0.61) | PTGER1MRGPRX4CYP2C9KMT2A | |
| SCHEMBL28506917 | 0.76 | MRGPRX4 (0.56) | PTGER1MRGPRX4CYP2C9 | |
| SCHEMBL1388211 | 0.76 | PTGER1 (0.60) | PTGER1MRGPRX4KMT2AFOLH1 | |
| SCHEMBL3814086 | 0.76 | PTGER1 (0.64) | PTGER1MRGPRX4CYP2C9KDM4EGAA | |
| SCHEMBL4722050 | 0.76 | PTGER1 (0.64) | PTGER1MRGPRX4CYP2C9KMT2A | |
| SCHEMBL29836110 | 0.76 | PTGER1 (0.64) | PTGER1MRGPRX4CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |