Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101665 | 0.83 | FABP5 (0.49) | ALDH1A1KMT2AFABP5FABP7TP53 | |
| SCHEMBL8593716 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2ATP53TAAR1MEN1 | |
| SCHEMBL6188895 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2ATP53TAAR1MEN1 | |
| SCHEMBL27547 | 0.74 | KMT2A (0.55) | ALDH1A1KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL29349891 | 0.74 | KMT2A (0.55) | ALDH1A1KMT2AFABP5FABP7EPHX2 | |
| Hydrochloric Acid SCHEMBL810434 | 0.73 | KMT2A (0.54) | ALDH1A1KMT2AFABP5FABP7EPHX2 | |
| Ammonia Solution, Strong SCHEMBL27794450 | 0.73 | KMT2A (0.54) | ALDH1A1KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL8103472 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KMT2ATP53TAAR1MEN1 | |
| SCHEMBL4602139 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL16420440 | 0.71 | EPHX2 (0.61) | ALDH1A1KMT2AFABP5FABP7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |