SCHEMBL8675331

SCHEMBL8675331

CCCCCCCCN=C=O.C[Si](Cl)(Cl)CCCN=C=O

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.42
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4531725 0.89 NAAA (0.30) NAAA
SCHEMBL4538365 0.89 NAAA (0.30) NAAA
SCHEMBL4534703 0.89 NAAA (0.30) NAAA
SCHEMBL4518850 0.89 NAAA (0.30) NAAA
SCHEMBL4527954 0.89 NAAA (0.30) NAAA
SCHEMBL4518595 0.89 NAAA (0.30) NAAA
SCHEMBL4528405 0.89 NAAA (0.30) NAAA
SCHEMBL4527121 0.89 NAAA (0.30) NAAA
SCHEMBL4522929 0.89 NAAA (0.30) NAAA
SCHEMBL4525055 0.89 NAAA (0.30) NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0880558-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1998-12-02 EP disclosed
WO-1998008839-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES ELI LILLY AND COMPANY (US) 1998-03-05 WO disclosed
WO-1998008813-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES ELI LILLY AND COMPANY (US) 1998-03-05 WO disclosed
WO-1997026300-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1997-07-24 WO disclosed