SCHEMBL8675342

SCHEMBL8675342

CCCCCC(=O)Oc1cccc(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.54
POLK Q9UBT6 2/20 0.54
POLL Q9UGP5 2/20 0.54
POLH Q9Y253 2/20 0.54
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
RECQL P46063 1/20 0.52
ALOX15 P16050 1/20 0.48
PPARG P37231 2/20 0.42
TOP2A P11388 2/20 0.41
EPHX2 P34913 1/20 0.41
HTR1D P28221 2/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
DRD1 P21728 1/20 0.41
HTR2A P28223 1/20 0.41
PPARA Q07869 1/20 0.41
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8676264 0.95 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL4573844 0.89 KMT2A (0.45) POLMPOLKPOLLPOLHKMT2A
SCHEMBL8676312 0.88 KDM4E (0.59) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15548447 0.87 POLM (0.53) POLMPOLKPOLLPOLHKMT2A
SCHEMBL5543128 0.86 ALOX15 (0.52) POLMPOLKPOLLPOLHKMT2A
SCHEMBL8088316 0.86 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL27508353 0.86 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL9322247 0.86 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15548023 0.85 POLM (0.55) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15547888 0.85 POLM (0.55) POLMPOLKPOLLPOLHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5728911-A CATALYTIC SOLUTION COPOLYMERIZATION OF ETHYLENE WITH POLYUNSATURATED MONOMER DSM COPOLYMER, INC. (US) 1998-03-17 US disclosed
EP-0705284-B1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1997-07-09 EP disclosed
EP-0705284-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1996-04-10 EP disclosed
WO-1995000564-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM N.V. (NL) 1995-01-05 WO disclosed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 EP disclosed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 US disclosed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 EP disclosed