SCHEMBL8675366

SCHEMBL8675366

c1ccc2cc(OCCOCOCCOc3ccc4ccccc4c3)ccc2c1

nearest known ligand 0.85

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.85
KDM4E B2RXH2 2/20 0.85
MAPK1 P28482 1/20 0.85
NPC1 O15118 3/20 0.71
RAB9A P51151 3/20 0.71
MAPT P10636 2/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
AGXT P21549 2/20 0.57
ALOX5 P09917 1/20 0.53
PPARG P37231 1/20 0.51
PTPN7 P35236 1/20 0.50
HTT P42858 1/20 0.50
HRH3 Q9Y5N1 4/20 0.49
DRD3 P35462 1/20 0.49
ALDH1A1 P00352 1/20 0.49
NCF1 P14598 3/20 0.49
HDAC1 Q13547 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15657734 0.92 TDP1 (1.00) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL8673201 0.92 TDP1 (1.00) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL8674825 0.92 TDP1 (1.00) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL16902851 0.89 TDP1 (0.87) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL28900533 0.85 TDP1 (0.79) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL2177291 0.83 KDM4E (0.77) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL16021984 0.83 KDM4E (0.82) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL16021974 0.83 KDM4E (0.82) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL20110893 0.83 TDP1 (0.82) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL13174723 0.83 KDM4E (0.82) TDP1KDM4EMAPK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5827796-A Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-10-27 US disclosed
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
US-4855278-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-08 US disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed