SCHEMBL8675409

SCHEMBL8675409

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nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
CYP2C9 P11712 1/20 0.43
PDE4A P27815 1/20 0.43
CPT2 P23786 1/20 0.41
ACLY P53396 1/20 0.41
PGD P52209 1/20 0.33
OR51E2 Q9H255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7534978 0.87 CPT2 (0.43) TSHRCYP2C9PDE4ACPT2ACLY
SCHEMBL5859283 0.84 TSHR (0.41) TSHRCYP2C9PDE4ACPT2ACLY
SCHEMBL30970938 0.79 PDE4A (0.43) PDE4ACPT2ACLYOR51E2
SCHEMBL2935030 0.74 CPT2 (0.39) PDE4ACPT2ACLYOR51E2
SCHEMBL21313126 0.74 CPT2 (0.39) PDE4ACPT2ACLYOR51E2
SCHEMBL27509647 0.73 SMN1; SMN2 (0.43) CYP2C9PDE4A
SCHEMBL722150 0.73 TSHR (0.43) TSHRCYP2C9PDE4ACPT2ACLY
SCHEMBL722576 0.73 ACLY (0.64) TSHRCYP2C9PDE4ACPT2ACLY
SCHEMBL22833252 0.73 TSHR (0.43) TSHRCYP2C9PDE4ACPT2ACLY
SCHEMBL5356598 0.73 TSHR (0.43) TSHRCYP2C9PDE4ACPT2ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5731467-A OXIDATIVE DEGRADATION OF 5-KETOGLUCONIC ACID IN ALKALINE MEDIUM ROQUETTE FRERES (FR) 1998-03-24 US disclosed