Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8677320 | 0.95 | GPR3 (0.43) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL6675583 | 0.95 | GPR3 (0.46) | GPR3POLBKMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL8676327 | 0.91 | GPR3 (0.43) | GPR3POLBKMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL8677327 | 0.91 | GPR3 (0.43) | GPR3POLBKMT2AMEN1ATM | |
| Iodide SCHEMBL8675592 | 0.91 | GPR3 (0.43) | GPR3POLBKMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL8676324 | 0.91 | GPR3 (0.43) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL27797255 | 0.80 | POLB (0.39) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL3919889 | 0.80 | GPR3 (0.46) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL4652201 | 0.78 | SLC6A2 (0.46) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL18729739 | 0.76 | CYP1A2 (0.44) | GPR3POLBKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712404-A | REACTION OF FULVENE TYPE COMPOUND, AN ALKALI METAL COMPOUND AND TRANSITION METAL COMPOUND FOR CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-27 | — | — | US | disclosed |