Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 12/20 | 0.48 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074253 | 0.81 | ANPEP (0.64) | FDPSANPEPGGPS1ERAP2MMP1 | |
| SCHEMBL8674573 | 0.78 | ANPEP (0.63) | FDPSANPEPERAP2LAP3MMP1 | |
| SCHEMBL13698880 | 0.78 | ANPEP (0.42) | FDPSANPEPGGPS1ERAP2LAP3 | |
| SCHEMBL7538729 | 0.78 | ANPEP (0.58) | FDPSANPEPGGPS1ERAP2MMP2 | |
| SCHEMBL4102805 | 0.77 | FDPS (0.39) | FDPSANPEPKDM4EERAP2MMP2 | |
| SCHEMBL11408514 | 0.76 | FDPS (0.56) | FDPSANPEPERAP2LAP3 | |
| SCHEMBL8674064 | 0.74 | ANPEP (0.69) | FDPSANPEPGGPS1ERAP2 | |
| SCHEMBL11418940 | 0.74 | ANPEP (0.69) | FDPSANPEPGGPS1ERAP2 | |
| SCHEMBL3059482 | 0.74 | ANPEP (0.69) | FDPSANPEPGGPS1ERAP2 | |
| SCHEMBL11056866 | 0.74 | ANPEP (0.58) | FDPSANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728650-A | Herbicidal aza bisphosphonic acids and compositions containing the same | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| US-4216163-A | SEQUESTERING AGENTS | BENCKISER-KNAPSACK GMBH (DE) | 1980-08-05 | — | — | US | disclosed |
| EP-0000930-A1 | N-Carboxyalkane-aminoalkane-diphosphonic acids, N-carboxyalkane-azacycloalkane-diphosphonic acids and N-carboxyalkane-aminoarylkane diphosphonic acids, process for their preparation and their use as sequestering agents | Benckiser-Knapsack GmbH (DE) | 1979-03-07 | — | — | EP | disclosed |