Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028620 | 1.00 | AVPR1A (0.55) | AVPR1AAVPR2OXTRAVPR1BGAA | |
| SCHEMBL8676668 | 0.92 | AVPR1A (0.61) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL9028217 | 0.92 | AVPR1A (0.61) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL9028294 | 0.90 | AVPR1A (0.58) | AVPR1AAVPR2OXTRAVPR1BGAA | |
| SCHEMBL8672321 | 0.90 | AVPR1A (0.58) | AVPR1AAVPR2OXTRAVPR1BGAA | |
| SCHEMBL9028504 | 0.87 | AVPR2 (0.54) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL8671336 | 0.87 | AVPR2 (0.54) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL9028609 | 0.86 | AVPR1A (0.51) | AVPR1AAVPR2OXTRAVPR1BGAA | |
| SCHEMBL9027824 | 0.85 | AVPR1A (0.59) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL8673860 | 0.85 | AVPR1A (0.59) | AVPR1AAVPR2OXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710150-A | ARGININE VASOPRESSIN ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |