Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.61 |
| ▸ | OXTR | P30559 | 2/20 | 0.55 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676668 | 1.00 | AVPR1A (0.61) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL8672321 | 0.94 | AVPR1A (0.58) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL9028294 | 0.94 | AVPR1A (0.58) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL8673860 | 0.92 | AVPR1A (0.59) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL9027824 | 0.92 | AVPR1A (0.59) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL9028620 | 0.92 | AVPR1A (0.55) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL8675689 | 0.92 | AVPR1A (0.55) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL9028739 | 0.91 | AVPR2 (0.58) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL8673863 | 0.91 | AVPR2 (0.58) | AVPR1AAVPR2OXTRAVPR1BMAPT | |
| SCHEMBL8677658 | 0.89 | AVPR1A (0.63) | AVPR1AAVPR2OXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716083-A1 | BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |