Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675783 | 1.00 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8672354 | 1.00 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8672351 | 1.00 | HTR1A (1.00) | HTR1A | |
| Hydrochloric Acid SCHEMBL7935369 | 0.99 | HTR1A (0.98) | HTR1A | |
| Hydrochloric Acid SCHEMBL7935391 | 0.99 | HTR1A (0.98) | HTR1A | |
| SCHEMBL8672064 | 0.89 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8675884 | 0.89 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8671073 | 0.89 | HTR1A (1.00) | HTR1A | |
| Hydrochloric Acid SCHEMBL7926403 | 0.88 | HTR1A (0.98) | HTR1A | |
| SCHEMBL8675801 | 0.88 | HTR1A (1.00) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2785879-B2 | — | — | 1998-08-13 | — | — | JP | claimed |
| EP-0476016-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| WO-1990015047-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | claimed |
| EP-0482084-B1 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | disclosed |