Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 14/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670718 | 0.85 | FDPS (0.50) | AAK1CYP3A4GSK3BDYRK1AIRAK4 | |
| SCHEMBL5251219 | 0.83 | EGFR (0.57) | AAK1GSK3BDYRK1AIRAK4CYP17A1 | |
| SCHEMBL9232528 | 0.83 | CYP17A1 (0.50) | AAK1CYP3A4GSK3BDYRK1AIRAK4 | |
| SCHEMBL12127932 | 0.82 | FDPS (0.54) | AAK1GSK3BDYRK1APIK3C3 | |
| SCHEMBL5544966 | 0.82 | CYP17A1 (0.47) | AAK1CYP3A4GSK3BDYRK1AIRAK4 | |
| SCHEMBL5251601 | 0.81 | GSK3B (0.46) | AAK1CYP3A4GSK3BDYRK1AIRAK4 | |
| SCHEMBL5548970 | 0.81 | ATR (0.48) | AAK1CYP3A4GSK3BDYRK1AIRAK4 | |
| SCHEMBL29992322 | 0.80 | AAK1 (0.48) | AAK1CYP3A4GSK3BDYRK1AIRAK4 | |
| SCHEMBL17643492 | 0.80 | AAK1 (0.48) | AAK1CYP3A4GSK3BDYRK1AIRAK4 | |
| SCHEMBL27955914 | 0.80 | ATR (0.42) | AAK1GSK3BDYRK1AIRAK4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |