Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188080 | 0.88 | VDR (0.61) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL13531914 | 0.88 | VDR (0.61) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL25894631 | 0.88 | VDR (0.59) | VDR | |
| SCHEMBL3186492 | 0.88 | VDR (0.60) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL8559729 | 0.86 | VDR (0.56) | VDRHDAC6HDAC3 | |
| SCHEMBL25314634 | 0.86 | VDR (0.56) | VDR | |
| SCHEMBL8090252 | 0.86 | VDR (0.56) | VDR | |
| SCHEMBL25895008 | 0.86 | VDR (0.56) | VDR | |
| SCHEMBL25314638 | 0.86 | VDR (0.56) | VDR | |
| SCHEMBL25410119 | 0.85 | VDR (0.53) | VDRHDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827883-A | TOPICAL DRUG DELIVERY; SIDE EFFECT REDUCTION | HOFFMANN-LA ROCHE INC. (US) | 1998-10-27 | — | — | US | disclosed |