Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222176 | 0.93 | KMT2A (0.58) | KMT2AL3MBTL1KDM4ERAB9ANPC1 | |
| SCHEMBL29625195 | 0.93 | KMT2A (0.58) | KMT2AL3MBTL1KDM4ERAB9ANPC1 | |
| SCHEMBL27761399 | 0.91 | KMT2A (0.57) | KMT2AL3MBTL1KDM4ERAB9ANPC1 | |
| Pyrrole SCHEMBL28037854 | 0.86 | KMT2A (0.54) | KMT2AL3MBTL1KDM4ERAB9ANPC1 | |
| Isophthalic Acid SCHEMBL3867184 | 0.80 | CA12 (0.60) | L3MBTL1HSD17B10HPGDCA12CA1 | |
| SCHEMBL11108445 | 0.80 | KMT2A (0.58) | KMT2AL3MBTL1KDM4ERAB9ANPC1 | |
| SCHEMBL7056764 | 0.79 | HPGD (0.59) | KMT2AL3MBTL1KDM4ERAB9ANPC1 | |
| SCHEMBL28555578 | 0.79 | KMT2A (0.47) | KMT2AL3MBTL1KDM4ERAB9ANPC1 | |
| SCHEMBL31412787 | 0.79 | CYP2C19 (0.46) | LMNAHSD17B10ALDH1A1HPGDCA12 | |
| SCHEMBL31412786 | 0.79 | CYP2C19 (0.46) | LMNAHSD17B10ALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707559-A | PROVIDING A STABLE 1,2-DIOXETANE WHICH FORMS INTERMEDIATE UNSTABLE COMPOUNDS WHEN TRIGGERED TO REMOVE BLOCKING GROUPS BY ACTIVATING AGENT SO THAT UNSTABLE COMPOUND DECOMPOSES TO FORM LIGHT AND TWO CARBONYL COMPOUNDS | TROPIX, INC. (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0595369-B1 | Alkene compounds | TROPIX INC (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5386017-A | Can be converted to stable aryl substituted 1,2-dioxetanes which decompose when activated to produce light and carbonyl compounds | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0254051-B1 | Chemiluminescent 1,2-dioxetane compounds | UNIV WAYNE STATE (US) | 1994-08-31 | — | — | EP | disclosed |
| EP-0595369-A1 | Alkene compounds | TROPIX, INC. (US) | 1994-05-04 | — | — | EP | disclosed |
| US-4962192-A | Chemiluminescent 1,2-dioxetane compounds | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4857652-A | Chemiluminescent 1,2-dioxetane compounds | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0254051-A2 | Chemiluminescent 1,2-dioxetane compounds | THE BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1988-01-27 | — | — | EP | disclosed |