SCHEMBL8677908

SCHEMBL8677908

C[SiH](C)[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C(c2ccccc2)=Cc2c(-c3cnc4ccccc4c3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.33
CREBBP Q92793 2/20 0.33
BIRC5 O15392 1/20 0.31
MAP4K4 O95819 1/20 0.31
CSNK1G2 P78368 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
MKNK2 Q9HBH9 1/20 0.31
MAP4K5 Q9Y4K4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8679081 0.90 BRD4 (0.34) BRD4CREBBPBIRC5MAP4K4CSNK1G2
SCHEMBL8675221 0.89 BIRC5 (0.37) BRD4CREBBPBIRC5MAP4K4CSNK1G2
SCHEMBL8677098 0.89 BRD4 (0.35) BRD4CREBBP
SCHEMBL8677214 0.88 BRD4 (0.33) BRD4CREBBP
SCHEMBL8679072 0.85 BRD4 (0.33) BRD4CREBBP
Hydrochloric Acid SCHEMBL8677912 0.84 BRD4 (0.34) BRD4CREBBPBIRC5MAP4K4CSNK1G2
SCHEMBL8675857 0.83 BRD4 (0.32) BRD4CREBBP
SCHEMBL8675796 0.82 BRD4 (0.33) BRD4CREBBP
SCHEMBL5953421 0.78 PARP10 (0.37) BRD4CREBBPBIRC5MAP4K4CSNK1G2
SCHEMBL8677341 0.78 BRD4 (0.34) BRD4CREBBPBIRC5MAP4K4CSNK1G2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840947-A Organometallic compound TARGOR GMBH (DE) 1998-11-24 US claimed
US-5840947-A Organometallic compound TARGOR GMBH (DE) 1998-11-24 US disclosed