SCHEMBL8679072

SCHEMBL8679072

CCCCC1=Cc2c(-c3cnc4ccccc4c3)cccc2C1[Zr](Cl)(Cl)(C1C=Cc2ccccc21)[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.33
CREBBP Q92793 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8677214 0.92 BRD4 (0.33) BRD4CREBBP
SCHEMBL8678066 0.90 BRD4 (0.36) BRD4CREBBP
SCHEMBL8679081 0.87 BRD4 (0.34) BRD4CREBBP
Hydrochloric Acid SCHEMBL8679075 0.86 BRD4 (0.33) BRD4CREBBP
SCHEMBL8677098 0.86 BRD4 (0.35) BRD4CREBBP
SCHEMBL8677908 0.85 BRD4 (0.33) BRD4CREBBP
SCHEMBL7198683 0.84
SCHEMBL7193818 0.83
SCHEMBL7194285 0.82
SCHEMBL7194162 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840947-A Organometallic compound TARGOR GMBH (DE) 1998-11-24 US claimed
US-5840947-A Organometallic compound TARGOR GMBH (DE) 1998-11-24 US disclosed