Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678382 | 0.91 | TLR7 (0.43) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8680399 | 0.83 | GCGR (0.39) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8677926 | 0.83 | GCGR (0.43) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8678404 | 0.83 | GCGR (0.43) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8137227 | 0.82 | CYP1A2 (0.43) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8135149 | 0.82 | TLR7 (0.42) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8678693 | 0.82 | TLR7 (0.42) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8677290 | 0.82 | TLR7 (0.43) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8677009 | 0.82 | TLR7 (0.40) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8678688 | 0.82 | KDM5B (0.40) | TLR7ALDH1A1KDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579424-B1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-23 | — | — | EP | claimed |
| US-5300477-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | claimed |
| CN-1084165-A | 2-Arylpyrimidines and weeding thereof are used | ROHM & HAAS (US) | 1994-03-23 | — | — | CN | claimed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | claimed |
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0579424-B1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0696588-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5453414-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5300477-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |